{"id":3843,"date":"2024-02-13T14:16:06","date_gmt":"2024-02-13T11:16:06","guid":{"rendered":"https:\/\/lveel.com.tr\/test\/?page_id=3843"},"modified":"2024-02-16T16:08:49","modified_gmt":"2024-02-16T13:08:49","slug":"lipozomal-biyoteknoloji","status":"publish","type":"page","link":"https:\/\/lveel.com.tr\/test\/lipozomal-biyoteknoloji\/","title":{"rendered":"Lipozomal Biyoteknoloji"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3843\" class=\"elementor elementor-3843\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b3e6052 e-flex e-con-boxed e-con e-parent\" data-id=\"b3e6052\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b2d7234 e-flex e-con-boxed e-con e-parent\" data-id=\"b2d7234\" data-element_type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\" data-core-v316-plus=\"true\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-445dcb0 elementor-widget elementor-widget-heading\" data-id=\"445dcb0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Lipozomal Biyoteknoloji<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a421c27 elementor-widget elementor-widget-text-editor\" data-id=\"a421c27\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.20.0 - 26-03-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h5><b>Lipozom nedir?<\/b><\/h5>\n<p>Lipozom ad\u0131 iki Yunanca kelimeden t\u00fcretilmi\u015ftir: Lipit, ya\u011f anlam\u0131na gelen \u2018Lipos\u2019 ve g\u00f6vde anlam\u0131na gelen \u2018Soma\u2019. Tarihte ilk kez 1961 y\u0131l\u0131nda Dr Alec D Bangham taraf\u0131ndan ke\u015ffedilmi\u015f ve 1964 y\u0131l\u0131nda yay\u0131nlanm\u0131\u015ft\u0131r.<\/p>\n<p>Fosfolipid i\u00e7erikli, h\u00fccre yap\u0131s\u0131na benzeyen, hidrofilik ve lipofilik k\u0131s\u0131mlar\u0131 olan amfifilik \u00f6zellikte , 30 nm \u2013 1000 nm aras\u0131ndaki ta\u015f\u0131y\u0131c\u0131 sistemlerdir.<\/p>\n<p>1970\u2019lerden bu yana bir\u00e7ok potansiyel avantaj\u0131 nedeniyle ila\u00e7 da\u011f\u0131t\u0131m sistemleri olarak incelenmi\u015ftir. 1995 Y\u0131l\u0131nda ise ilk kez lipozomal teknoloji, kanser tedavisinde FDA onayl\u0131 Doxil\u00ae ilac\u0131 ile uygulanm\u0131\u015ft\u0131r.<\/p>\n<p>Lipozomal biyoteknoloji, h\u00fccreye \u00e7ok benzer yap\u0131lar olu\u015fturarak etken maddenin v\u00fccut i\u00e7inde etkili bir \u015fekilde da\u011f\u0131t\u0131m\u0131n\u0131 sa\u011flayan teknolojidir. Olu\u015fturulan bu yap\u0131lara lipozom k\u00fcrecikleri denir. Lipozom k\u00fcrecikleri, etken maddenin \u00e7ift katl\u0131 fosfolipid tabakas\u0131 ile \u00e7evrelenmesiyle olu\u015furlar.<\/p>\n<p>Fosfolipidler, v\u00fccudumuzdaki h\u00fccre zarlar\u0131n\u0131n ana bile\u015fenlerindendir. Yani lipozomal k\u00fcrecikler, do\u011fal h\u00fccre zarlar\u0131n\u0131 taklit ederler. Etken maddenin d\u0131\u015f\u0131ndaki bu fosfolipid tabakas\u0131, v\u00fccuttaki enzimler veya pH seviyelerindeki de\u011fi\u015fim sebepli etken maddenin bozulmas\u0131n\u0131n \u00f6n\u00fcne ge\u00e7er. B\u00f6ylece lipozomal biyoteknoloji etkinin iyile\u015ftirilmesine ve uzat\u0131lmas\u0131na katk\u0131da bulunur.<\/p>\n<p>Lipozomal biyoteknoloji ile;<br><ul><li>Etken maddenin emilimi dolay\u0131s\u0131yla etkinli\u011fi artar.<\/li><li>Fosfolipid tabaka sayesinde stabilite artar.<\/li><li>Yan etki olu\u015fumunu engeller.<\/li><li>Aktif hedeflemeye imkan sa\u011flar.&nbsp;<\/li><\/ul><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Lipozom nedir? Lipozom ad\u0131 iki Yunanca kelimeden t\u00fcretilmi\u015ftir: Lipit, ya\u011f anlam\u0131na gelen \u2018Lipos\u2019 ve g\u00f6vde anlam\u0131na gelen \u2018Soma\u2019. Tarihte ilk kez 1961 y\u0131l\u0131nda Dr Alec D Bangham taraf\u0131ndan ke\u015ffedilmi\u015f ve 1964 y\u0131l\u0131nda yay\u0131nlanm\u0131\u015ft\u0131r. Fosfolipid i\u00e7erikli, h\u00fccre yap\u0131s\u0131na benzeyen, hidrofilik ve lipofilik k\u0131s\u0131mlar\u0131 olan amfifilik \u00f6zellikte , 30 nm \u2013 1000 nm aras\u0131ndaki ta\u015f\u0131y\u0131c\u0131 sistemlerdir. 1970\u2019lerden [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[],"class_list":["post-3843","page","type-page","status-publish","hentry"],"lang":"tr","translations":{"tr":3843,"en":4089,"ru":4625,"de":4847},"pll_sync_post":[],"_links":{"self":[{"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/pages\/3843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/comments?post=3843"}],"version-history":[{"count":19,"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/pages\/3843\/revisions"}],"predecessor-version":[{"id":3999,"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/pages\/3843\/revisions\/3999"}],"wp:attachment":[{"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/media?parent=3843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lveel.com.tr\/test\/wp-json\/wp\/v2\/categories?post=3843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}